With rising incidence of diabetes mellitus in Nepalese population, it is crucial that a harmonized nation-wide
definition of protocols for fasting blood glucose testing be worked out and adopted urgently to minimize the
current discrepancies in the results reported by different clinical laboratories of Nepal.
Angimyomatous hamartoma (AMH) is a very rare, benign disease of lymph node characterized by parenchymal replacement of nodal
structure with fibrous tissue containing proliferative blood vessels and smooth muscle
The aim of the present article is to aware healthcare providers about the factors that can cause FBG level higher than PPBG.
It is rare to get the same results when a sample of the individual is measured at different times, even if the state of health in the individual has not been changed. If such difference in test results from repeated testing is observed, physicians and health care professionals should also be aware of possible factors other than laboratory error.
In a Nepalese population, there is better agreement of the Friedewald formula with a directly measured LDL-C compared to the de
Cordova formula. However, this has to be verified in a larger population, including different conditions in which the Friedewald formula
was found to be inaccurate.
Blood glucose measurement in serum can be accepted if the serum separation via centrifugation is achieved within 30 minutes. The avoidance of an extra amount of blood draw in a separate NaF tube and better turn-around-time are advantages of using serum tubes. It should be mandatory to have a centrifuge at all collection centers to achieve blood separation within a reasonable time.
Hemoglobin fraction analysis by ion-exchange in HPLC has the advantage of quantifying HbF and
HbA2 along with hemoglobin variant screening in a single reproducible system making it an excellent tool to screen for hemoglobin variants and hemoglobinopathy.
It is justifiable to screen for blood-lead levels in the reproductive age group individual in Nepal. Policymakers
are encouraged to review recommendations of other organizations, including national scientific publications
regarding lead and its health hazard.
Lead is a heavy metal ubiquitous in our environment which has no physiological role in biological systems. It s rather a cumulative toxicant that affects multiple body systems and is particularly harmful to young children. Its widespread use has resulted in extensive human exposure and significant public health problems in many parts of the world.
An association between the risk of a miscarriage and anti TPO antibodies has been largely confirmed in several population studies even in absence of overt thyroid dysfunction.
Patients having persistently raised AST level without other abnormal liver indices should be tested for macroAST. Early diagnosis of macroAST avoids unnecessary investigations or invasive procedures and decreases patient anxiety.