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Reference values differ with the menstrual cycle phase. Lower values are seen after menopause.
INCREASE IN:
In Female: Early (precocious) puberty, Tumors of the ovary or adrenal glands, Hyperthyroidism Cirrhosis
In Male: Enlarged breasts (gynecomastia), Tumors of the testicles (testicular cancer) or adrenal glands, Delayed puberty.
DECREASE IN: Turner syndrome, hypopituitarism, female hypogonadism, menopause