Also Known As: Alpha feto-protein
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Alpha-fetoprotein (AFP) is a glycoprotein that is produced in early fetal life by the liver and by a variety of tumors including hepatocellular carcinoma, hepatoblastoma, and non seminomatous germ cell tumors of the ovary and testis.
Intended only as an adjunct to diagnose and monitor therapy for certain cancers of the liver, testicles, or ovaries. For pregnant women, to assess the risk of having a baby with certain chromosomal disorders, such as Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18), or open neural tube defects.
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REFERENCE INTERVALS FOR ADULTS: - <7.22 IU/mL.
INCREASE IN: Liver cancer, cancer of the ovary, germ cell tumor of the testicles, cirrhosis, hepatitis, other cancers such as stomach, colon, lung, breast, and lymphoma.
DECREASE IN: NA